Einleitung

Product Features

Indications

Biopsy Technique

Implantation Technique

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BioSeed^®-C, the autologous 3-dimensional chondrocyte graft with a unique shape for primary mechanical stability. Used successfully since 2002 to treat degenerative and traumatic articular cartilage defects and proven with 4 years clinical follow-up in the treatment of osteoarthritis.

• Patented, stable 3D matrix
• Unique, secure fixation by arthroscopy or arthrotomy (e.g. with absorbable pins)
• Stable form and shape
• Treatment of single and multiple, traumatic and degenerative defects with sub-optimal surrounding cartilage measuring more than 1.5 cm²
• Size: 30 mm x 20 mm x 2 mm
• Approx. 20x10⁶ cells per cm³
• GMP manufacturing
• Flexible scheduling for transplantation
• Delivered throughout Europe
• Implantation 3-4 weeks after cartilage biopsy
• More than 1000 patients successfully treated

Thanks to autologous chondrocyte transplantation with a stable 3D matrix, knee injuries (femoral condyle, tibia plateau, patella), ankle injuries (talus) or hip injuries (acetabulum) can be treated with the patient’s own cells.

The matrix used consists of two components: a polymer carrier fleece which forms the framework structure and a biological “glue” which fixes the homogenously distributed chondrocytes in the carrier fleece. This combination provides the chondrocytes with an ideal three-dimensional environment which stimulates them to redifferentiate and thus assume their original morphology and function.

As a result, the graft itself is mechanically stable, supple, flexible and can be cut to fit the size of the defect.

BioSeed^®-C is produced in a GMP laboratory according to strict manufacturing criteria.

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